Results matching “PSP” from Research in Psychosomatic Medicine

 Somatic symptoms of medically unknown origin are highly prevalent in the community and clinical settings.  Functional somatic syndrome (FSS) refers to several related syndromes that are characterized more by symptoms, suffering, and disability than by demonstrable abnormalities.  Two aspects should be considered in the underlying pathophysiology of FSS: dysregulation of the stress response in autonomic nervous systems and psychological factors that modulate the expression of symptoms.

 Psychophysiological Stress Profiling (PSP) is a method of estimating the response to a stress by measuring multiple physiological parameters and psychological indices.
Physiological indices were hypo-reactive to mental work stress and psychological tension was high in the FSS compared with controls.  These findings suggest FSS patients have hypo-functional stress responses, and couldn't cope with the stress properly.

Table2_PSPMeasurements.pdf

<Physiological Measurements>
  The measurement of PSP was made using the ProComp Infinity™/ BioGraph Infinity (Thought Technology Ltd., Montreal) biofeedback system.  The following indices were measured (Table 2).

<Psychological Measurements>
  To evaluate the temporary mood states, the Profile of Mood States (POMS) test was administered. The POMS assesses six affective mood dimensions: tension-anxiety (TA), depression-dejection (D), anger-hostility (A), vigor-activity (V), fatigue-inertia (F), and confusion-bewilderment(C).

  The subjective symptom score (subjective severity of symptoms) and the subjective tension score (subjective feelings of tension) were also obtained using a visual analogue scale.

 
<Procedure>
  After the psychological measurements were administered, the physiological measurements were made during the following three periods (5 minutes each, total of 15 minutes).  The subject was seated in a chair with eyes closed.

a) Baseline resting period: the subject was instructed to relax and make himself/ herself comfortable
b) Stress period (mental arithmetic task): the subject was instructed to subtract 7 serially from 1000.
c) Post stress period: the subject was instructed to relax.

  The origin of functional somatic symptoms cannot be detected by regular medical examination, because the abnormalities don't accompany visual changes typically.  Moreover, functional somatic symptoms are involved in stress.  Considering these things and pathophysiology, we evaluated the response of ANS-related physiological parameters to stress.

  Psychophysiological stress profiling (PSP) is a method of estimating the response to a stress by simultaneously measuring multiple physiological parameters based on the concept of autonomic response specificity (7,8).  PSP also include psychological measurements as we consider both pathophysiology a) and b) above.

  Although FSS are common worldwide and in all areas of medicine, diagnostic and therapeutic approaches are still controversial and not confirmed.

  Several studies as to the concept and the structure of the syndrome have been performed using questionnaire or interview (9,13,14).  Wessely et al. reviewed literatures and concluded that the similarities between individual syndromes outweigh the differences (4).  A meta-analytic review confirmed that FSSs are related to anxiety and depression but relatively independent to them (10).  Henningsen et al. reviewed management of FSS on literatures and recommended that a balance between biomedical (somatic) and interpersonal (psychological) approaches is important (5).

  There have been several studies of the PSP on individual syndromes such as irritable bowel syndrome or fibromyalgia syndrome, but few studies on FSS as a whole.  The bias of disease is small in our series of studies, so the findings could suggest the pathology of whole FSS independent upon diagnostic category.

  The relationship between objective assessment and subjective symptoms or feelings is important in FSS.  But almost studies are based on either objective or subjective index.

  Both objective assessment, i.e. physiological measuring, and subjective feelings, i.e. subjective score or psychological questionnaire, were used in our studies.  Relationship between them was also estimated.